Entity Details

Primary name CXCR2
Entity type gene
Source Source Link

Details

PrimaryID3579
RefseqGeneNG_052975
SymbolCXCR2
NameC-X-C motif chemokine receptor 2
Chromosome2
Location2q35
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-11-27
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsCXCR2_HUMAN

GO terms

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GOName
GO:0002407 dendritic cell chemotaxis
GO:0004918 interleukin-8 receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0006968 cellular defense response
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0008284 positive regulation of cell population proliferation
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
GO:0016493 C-C chemokine receptor activity
GO:0016494 C-X-C chemokine receptor activity
GO:0019722 calcium-mediated signaling
GO:0019957 C-C chemokine binding
GO:0019959 interleukin-8 binding
GO:0030593 neutrophil chemotaxis
GO:0030667 secretory granule membrane
GO:0031623 receptor internalization
GO:0038112 interleukin-8-mediated signaling pathway
GO:0042119 neutrophil activation
GO:0042629 mast cell granule
GO:0043312 neutrophil degranulation
GO:0060326 cell chemotaxis
GO:0072686 mitotic spindle

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CXCR2Cd74IntAct17435771 details