Entity Details

Primary name ATG7_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9D906
EntryNameATG7_MOUSE
FullNameUbiquitin-like modifier-activating enzyme ATG7
TaxID10090
Evidenceevidence at protein level
Length698
SequenceStatuscomplete
DateCreated2005-03-29
DateModified2021-06-02

Ontological Relatives

GenesAtg7

GO terms

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GOName
GO:0000045 autophagosome assembly
GO:0000407 phagophore assembly site
GO:0000422 autophagy of mitochondrion
GO:0001889 liver development
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005930 axoneme
GO:0006497 protein lipidation
GO:0006501 C-terminal protein lipidation
GO:0006914 autophagy
GO:0006995 cellular response to nitrogen starvation
GO:0006996 organelle organization
GO:0007005 mitochondrion organization
GO:0007628 adult walking behavior
GO:0008134 transcription factor binding
GO:0009267 cellular response to starvation
GO:0009791 post-embryonic development
GO:0010508 positive regulation of autophagy
GO:0015031 protein transport
GO:0016236 macroautophagy
GO:0019778 Atg12 activating enzyme activity
GO:0019779 Atg8 activating enzyme activity
GO:0021680 cerebellar Purkinje cell layer development
GO:0021860 pyramidal neuron development
GO:0021955 central nervous system neuron axonogenesis
GO:0021987 cerebral cortex development
GO:0030163 protein catabolic process
GO:0030424 axon
GO:0031175 neuron projection development
GO:0031396 regulation of protein ubiquitination
GO:0031401 positive regulation of protein modification process
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032446 protein modification by small protein conjugation
GO:0034614 cellular response to reactive oxygen species
GO:0034727 piecemeal microautophagy of the nucleus
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0039521 suppression by virus of host autophagy
GO:0039689 negative stranded viral RNA replication
GO:0042594 response to starvation
GO:0042752 regulation of circadian rhythm
GO:0042803 protein homodimerization activity
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0044805 late nucleophagy
GO:0045732 positive regulation of protein catabolic process
GO:0048471 perinuclear region of cytoplasm
GO:0048511 rhythmic process
GO:0050765 negative regulation of phagocytosis
GO:0050877 nervous system process
GO:0051607 defense response to virus
GO:0055013 cardiac muscle cell development
GO:0060284 regulation of cell development
GO:0060548 negative regulation of cell death
GO:0061024 membrane organization
GO:0061684 chaperone-mediated autophagy
GO:0070257 positive regulation of mucus secretion
GO:0071455 cellular response to hyperoxia
GO:0075044 positive regulation by symbiont of host autophagy
GO:0080144 amino acid homeostasis
GO:0090155 negative regulation of sphingolipid biosynthetic process
GO:0090156 cellular sphingolipid homeostasis
GO:0090298 negative regulation of mitochondrial DNA replication
GO:1901214 regulation of neuron death
GO:1903204 negative regulation of oxidative stress-induced neuron death
GO:1903706 regulation of hemopoiesis
GO:2000619 negative regulation of histone H4-K16 acetylation

Subcellular Location

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Subcellular Location
Cytoplasm
Preautophagosomal structure

Domains

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DomainNameCategoryType
IPR000594 THIF-type NAD/FAD binding foldDomainDomain
IPR006285 Ubiquitin-like modifier-activating enzyme Atg7FamilyFamily
IPR032197 Ubiquitin-like modifier-activating enzyme Atg7, N-terminalDomainDomain
IPR035985 Ubiquitin-activating enzymeFamilyHomologous superfamily
IPR042522 Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1FamilyHomologous superfamily
IPR042523 Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2FamilyHomologous superfamily

Diseases

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