Entity Details

Primary name INPP5D
Entity type gene
Source Source Link

Details

PrimaryID3635
RefseqGeneNG_033988
SymbolINPP5D
Nameinositol polyphosphate-5-phosphatase D
Chromosome2
Location2q37.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSHIP1_HUMAN

GO terms

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GOName
GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0004445 inositol-polyphosphate 5-phosphatase activity
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0006661 phosphatidylinositol biosynthetic process
GO:0006796 phosphate-containing compound metabolic process
GO:0006915 apoptotic process
GO:0007165 signal transduction
GO:0008340 determination of adult lifespan
GO:0009968 negative regulation of signal transduction
GO:0016064 immunoglobulin mediated immune response
GO:0017124 SH3 domain binding
GO:0019221 cytokine-mediated signaling pathway
GO:0030889 negative regulation of B cell proliferation
GO:0032715 negative regulation of interleukin-6 production
GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
GO:0035556 intracellular signal transduction
GO:0043065 positive regulation of apoptotic process
GO:0043647 inositol phosphate metabolic process
GO:0045121 membrane raft
GO:0045579 positive regulation of B cell differentiation
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045656 negative regulation of monocyte differentiation
GO:0045659 negative regulation of neutrophil differentiation
GO:0045671 negative regulation of osteoclast differentiation
GO:0045779 negative regulation of bone resorption
GO:0046856 phosphatidylinositol dephosphorylation
GO:0050777 negative regulation of immune response
GO:0050852 T cell receptor signaling pathway
GO:0050900 leukocyte migration
GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity
GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
INPP5DDok3MINT14993273 details
INPP5DSlamf7UniProt19151721 details