Entity Details

Primary name INSR
Entity type gene
Source Source Link

Details

PrimaryID3643
RefseqGeneNG_008852
SymbolINSR
Nameinsulin receptor
Chromosome19
Location19p13.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsINSR_HUMAN

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001540 amyloid-beta binding
GO:0001934 positive regulation of protein phosphorylation
GO:0002092 positive regulation of receptor internalization
GO:0003007 heart morphogenesis
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005009 insulin-activated receptor activity
GO:0005159 insulin-like growth factor receptor binding
GO:0005198 structural molecule activity
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0005764 lysosome
GO:0005770 late endosome
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005899 insulin receptor complex
GO:0005901 caveola
GO:0005975 carbohydrate metabolic process
GO:0006355 regulation of transcription, DNA-templated
GO:0006468 protein phosphorylation
GO:0006898 receptor-mediated endocytosis
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007275 multicellular organism development
GO:0007612 learning
GO:0007613 memory
GO:0008284 positive regulation of cell population proliferation
GO:0008286 insulin receptor signaling pathway
GO:0009897 external side of plasma membrane
GO:0010008 endosome membrane
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 membrane
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019087 transformation of host cell by virus
GO:0019904 protein domain specific binding
GO:0030335 positive regulation of cell migration
GO:0030424 axon
GO:0031994 insulin-like growth factor I binding
GO:0031995 insulin-like growth factor II binding
GO:0032147 activation of protein kinase activity
GO:0032148 activation of protein kinase B activity
GO:0032590 dendrite membrane
GO:0032809 neuronal cell body membrane
GO:0032869 cellular response to insulin stimulus
GO:0033674 positive regulation of kinase activity
GO:0038024 cargo receptor activity
GO:0042593 glucose homeostasis
GO:0042802 identical protein binding
GO:0043235 receptor complex
GO:0043243 positive regulation of protein-containing complex disassembly
GO:0043410 positive regulation of MAPK cascade
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0043559 insulin binding
GO:0043560 insulin receptor substrate binding
GO:0044877 protein-containing complex binding
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045725 positive regulation of glycogen biosynthetic process
GO:0045821 positive regulation of glycolytic process
GO:0045840 positive regulation of mitotic nuclear division
GO:0045995 regulation of embryonic development
GO:0046326 positive regulation of glucose import
GO:0046777 protein autophosphorylation
GO:0048639 positive regulation of developmental growth
GO:0051425 PTB domain binding
GO:0051897 positive regulation of protein kinase B signaling
GO:0060267 positive regulation of respiratory burst
GO:0070062 extracellular exosome
GO:0097062 dendritic spine maintenance
GO:0097242 amyloid-beta clearance
GO:0150104 transport across blood-brain barrier
GO:1990535 neuron projection maintenance

Diseases

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Interactions

8 interactions