Entity Details

Primary name KDM6A_MOUSE
Entity type UniProt
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Details

AccessionO70546
EntryNameKDM6A_MOUSE
FullNameLysine-specific demethylase 6A
TaxID10090
Evidenceevidence at protein level
Length1401
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesKdm6a

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001701 in utero embryonic development
GO:0001843 neural tube closure
GO:0003007 heart morphogenesis
GO:0003016 respiratory system process
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006338 chromatin remodeling
GO:0007507 heart development
GO:0010468 regulation of gene expression
GO:0010628 positive regulation of gene expression
GO:0021915 neural tube development
GO:0031490 chromatin DNA binding
GO:0032525 somite rostral/caudal axis specification
GO:0035097 histone methyltransferase complex
GO:0035264 multicellular organism growth
GO:0042802 identical protein binding
GO:0044666 MLL3/4 complex
GO:0046872 metal ion binding
GO:0048333 mesodermal cell differentiation
GO:0048568 embryonic organ development
GO:0048570 notochord morphogenesis
GO:0051213 dioxygenase activity
GO:0060070 canonical Wnt signaling pathway
GO:0071557 histone H3-K27 demethylation
GO:0071558 histone demethylase activity (H3-K27 specific)
GO:0072359 circulatory system development

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR003347 JmjC domainDomainDomain
IPR011990 Tetratricopeptide-like helical domain superfamilyFamilyHomologous superfamily
IPR019734 Tetratricopeptide repeatRepeatRepeat

Diseases

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Interactions

4 interactions