Entity Details

Primary name ITGA5
Entity type gene
Source Source Link

Details

PrimaryID3678
RefseqGene
SymbolITGA5
Nameintegrin subunit alpha 5
Chromosome12
Location12q13.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-02-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsITA5_HUMAN

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001618 virus receptor activity
GO:0001726 ruffle
GO:0005154 epidermal growth factor receptor binding
GO:0005161 platelet-derived growth factor receptor binding
GO:0005178 integrin binding
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0007044 cell-substrate junction assembly
GO:0007155 cell adhesion
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007159 leukocyte cell-cell adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0007565 female pregnancy
GO:0007613 memory
GO:0008305 integrin complex
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010811 positive regulation of cell-substrate adhesion
GO:0023035 CD40 signaling pathway
GO:0030198 extracellular matrix organization
GO:0030335 positive regulation of cell migration
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031410 cytoplasmic vesicle
GO:0031589 cell-substrate adhesion
GO:0033627 cell adhesion mediated by integrin
GO:0033631 cell-cell adhesion mediated by integrin
GO:0034113 heterotypic cell-cell adhesion
GO:0034674 integrin alpha5-beta1 complex
GO:0035313 wound healing, spreading of epidermal cells
GO:0035987 endodermal cell differentiation
GO:0043184 vascular endothelial growth factor receptor 2 binding
GO:0045202 synapse
GO:0046872 metal ion binding
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050900 leukocyte migration
GO:0071062 alphav-beta3 integrin-vitronectin complex
GO:1903672 positive regulation of sprouting angiogenesis
GO:2000811 negative regulation of anoikis

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ITGA5Nrp1DIP19175293 details
ITGA5Plpp3MINT16099422 details
ITGA5Itgb1BioGRID, IntAct26496610 details