Entity Details

Primary name ITGAV
Entity type gene
Source Source Link

Details

PrimaryID3685
RefseqGene
SymbolITGAV
Nameintegrin subunit alpha V
Chromosome2
Location2q32.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-02-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsITAV_HUMAN

GO terms

Show/Hide Table
GOName
GO:0001525 angiogenesis
GO:0001570 vasculogenesis
GO:0001618 virus receptor activity
GO:0001846 opsonin binding
GO:0001968 fibronectin binding
GO:0002020 protease binding
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005080 protein kinase C binding
GO:0005178 integrin binding
GO:0005245 voltage-gated calcium channel activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005925 focal adhesion
GO:0007155 cell adhesion
GO:0007160 cell-matrix adhesion
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007229 integrin-mediated signaling pathway
GO:0008284 positive regulation of cell population proliferation
GO:0008305 integrin complex
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010888 negative regulation of lipid storage
GO:0015026 coreceptor activity
GO:0016020 membrane
GO:0030198 extracellular matrix organization
GO:0030335 positive regulation of cell migration
GO:0031258 lamellipodium membrane
GO:0031527 filopodium membrane
GO:0031528 microvillus membrane
GO:0031589 cell-substrate adhesion
GO:0032369 negative regulation of lipid transport
GO:0032587 ruffle membrane
GO:0033627 cell adhesion mediated by integrin
GO:0033690 positive regulation of osteoblast proliferation
GO:0034113 heterotypic cell-cell adhesion
GO:0034446 substrate adhesion-dependent cell spreading
GO:0034683 integrin alphav-beta3 complex
GO:0034684 integrin alphav-beta5 complex
GO:0034685 integrin alphav-beta6 complex
GO:0034686 integrin alphav-beta8 complex
GO:0035579 specific granule membrane
GO:0035866 alphav-beta3 integrin-PKCalpha complex
GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex
GO:0035868 alphav-beta3 integrin-HMGB1 complex
GO:0035987 endodermal cell differentiation
GO:0038027 apolipoprotein A-I-mediated signaling pathway
GO:0043277 apoptotic cell clearance
GO:0043312 neutrophil degranulation
GO:0045335 phagocytic vesicle
GO:0045785 positive regulation of cell adhesion
GO:0046718 viral entry into host cell
GO:0046872 metal ion binding
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0050431 transforming growth factor beta binding
GO:0050748 negative regulation of lipoprotein metabolic process
GO:0050764 regulation of phagocytosis
GO:0050840 extracellular matrix binding
GO:0050900 leukocyte migration
GO:0050919 negative chemotaxis
GO:0070062 extracellular exosome
GO:0070371 ERK1 and ERK2 cascade
GO:0070588 calcium ion transmembrane transport
GO:0071604 transforming growth factor beta production
GO:0085017 entry into host cell by a symbiont-containing vacuole
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:1901388 regulation of transforming growth factor beta activation
GO:1905598 negative regulation of low-density lipoprotein receptor activity
GO:1990430 extracellular matrix protein binding
GO:2000536 negative regulation of entry of bacterium into host cell
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway

Diseases

Show/Hide Table

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
ITGAVFndc5BioGRID30550785 details
ITGAVPlpp3MINT16099422 details
ITGAVItgb1BioGRID, IntAct26496610 details
ITGAVEif3iBioGRID, IntAct26496610 details