Entity Details

Primary name ARAF
Entity type gene
Source Source Link

Details

PrimaryID369
RefseqGeneNG_016339
SymbolARAF
NameA-Raf proto-oncogene, serine/threonine kinase
ChromosomeX
LocationXp11.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-03-30
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsARAF_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005524 ATP binding
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006464 cellular protein modification process
GO:0032006 regulation of TOR signaling
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0043066 negative regulation of apoptotic process
GO:0046872 metal ion binding
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
ARAFMad2l1BioGRID, IntAct26496610 details
ARAFCdc37BioGRID, IntAct26496610 details
ARAFXpo1IntAct26673895 details
ARAFBub1BioGRID26496610 details