Entity Details

Primary name ITK
Entity type gene
Source Source Link

Details

PrimaryID3702
RefseqGeneNG_016276
SymbolITK
NameIL2 inducible T cell kinase
Chromosome5
Location5q33.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-06
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsITK_HUMAN

GO terms

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GOName
GO:0001819 positive regulation of cytokine production
GO:0001865 NK T cell differentiation
GO:0002250 adaptive immune response
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0006968 cellular defense response
GO:0007165 signal transduction
GO:0007202 activation of phospholipase C activity
GO:0035556 intracellular signal transduction
GO:0038083 peptidyl-tyrosine autophosphorylation
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0042110 T cell activation
GO:0046629 gamma-delta T cell activation
GO:0046872 metal ion binding
GO:0050852 T cell receptor signaling pathway
GO:0050853 B cell receptor signaling pathway

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ITKMbpBioGRID18067320 details