Entity Details

Primary name JUP
Entity type gene
Source Source Link

Details

PrimaryID3728
RefseqGeneNG_009090
SymbolJUP
Namejunction plakoglobin
Chromosome17
Location17q21.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1991-09-17
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsPLAK_HUMAN

GO terms

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GOName
GO:0001533 cornified envelope
GO:0001954 positive regulation of cell-matrix adhesion
GO:0002159 desmosome assembly
GO:0003713 transcription coactivator activity
GO:0005198 structural molecule activity
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005882 intermediate filament
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005915 zonula adherens
GO:0005916 fascia adherens
GO:0005925 focal adhesion
GO:0009898 cytoplasmic side of plasma membrane
GO:0014704 intercalated disc
GO:0015629 actin cytoskeleton
GO:0016327 apicolateral plasma membrane
GO:0016328 lateral plasma membrane
GO:0016342 catenin complex
GO:0016477 cell migration
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0030018 Z disc
GO:0030057 desmosome
GO:0031424 keratinization
GO:0032993 protein-DNA complex
GO:0034332 adherens junction organization
GO:0035580 specific granule lumen
GO:0042127 regulation of cell population proliferation
GO:0042307 positive regulation of protein import into nucleus
GO:0042803 protein homodimerization activity
GO:0043312 neutrophil degranulation
GO:0043537 negative regulation of blood vessel endothelial cell migration
GO:0044877 protein-containing complex binding
GO:0045294 alpha-catenin binding
GO:0045296 cadherin binding
GO:0045766 positive regulation of angiogenesis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050839 cell adhesion molecule binding
GO:0050982 detection of mechanical stimulus
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0070062 extracellular exosome
GO:0070268 cornification
GO:0071603 endothelial cell-cell adhesion
GO:0071665 gamma-catenin-TCF7L2 complex
GO:0071681 cellular response to indole-3-methanol
GO:0072659 protein localization to plasma membrane
GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication
GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
GO:0086091 regulation of heart rate by cardiac conduction
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0098609 cell-cell adhesion
GO:0098911 regulation of ventricular cardiac muscle cell action potential
GO:0106006 cytoskeletal protein-membrane anchor activity
GO:1904813 ficolin-1-rich granule lumen

Diseases

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Interactions

18 interactions

InteractorPartnerSourcesPublicationsLink
JUPCtnna1mbinfo9264463 details
JUPWwtr1IntAct23245942 details
JUPCdh1BioGRID, IntAct12847106 26496610 details
JUPDsc1BioGRID12847106 details
JUPDsg1aBioGRID12847106 details
JUPPpp1cbBioGRID, IntAct26496610 details
JUPBmpr1aBioGRID, IntAct26496610 details
JUPRab5cBioGRID, IntAct26496610 details
JUPMyh10BioGRID, IntAct26496610 details
JUPChmp4bBioGRID, IntAct26496610 details
JUPFlnbBioGRID, IntAct26496610 details
JUPCobll1BioGRID, IntAct26496610 details
JUPTmod3BioGRID, IntAct26496610 details
JUPTpm1BioGRID, IntAct26496610 details
JUPCoro1cBioGRID, IntAct26496610 details
JUPMyh9BioGRID, IntAct26496610 details
JUPNhsl1BioGRID, IntAct26496610 details
JUPFlot1BioGRID26496610 details