Entity Details

Primary name KIT
Entity type gene
Source Source Link

Details

PrimaryID3815
RefseqGeneNG_007456
SymbolKIT
NameKIT proto-oncogene, receptor tyrosine kinase
Chromosome4
Location4q12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-03-30
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsKIT_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000187 obsolete activation of MAPK activity
GO:0001541 ovarian follicle development
GO:0001650 fibrillar center
GO:0001669 acrosomal vesicle
GO:0002020 protease binding
GO:0002244 hematopoietic progenitor cell differentiation
GO:0002318 myeloid progenitor cell differentiation
GO:0002320 lymphoid progenitor cell differentiation
GO:0002327 immature B cell differentiation
GO:0002551 mast cell chemotaxis
GO:0002732 positive regulation of dendritic cell cytokine production
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005020 stem cell factor receptor activity
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006687 glycosphingolipid metabolic process
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0008284 positive regulation of cell population proliferation
GO:0008354 germ cell migration
GO:0008360 regulation of cell shape
GO:0008542 visual learning
GO:0008584 male gonad development
GO:0009897 external side of plasma membrane
GO:0009898 cytoplasmic side of plasma membrane
GO:0010863 positive regulation of phospholipase C activity
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019221 cytokine-mediated signaling pathway
GO:0019827 stem cell population maintenance
GO:0019955 cytokine binding
GO:0030032 lamellipodium assembly
GO:0030097 hemopoiesis
GO:0030183 B cell differentiation
GO:0030217 T cell differentiation
GO:0030218 erythrocyte differentiation
GO:0030318 melanocyte differentiation
GO:0030335 positive regulation of cell migration
GO:0031274 positive regulation of pseudopodium assembly
GO:0031532 actin cytoskeleton reorganization
GO:0032765 positive regulation of mast cell cytokine production
GO:0033674 positive regulation of kinase activity
GO:0035019 somatic stem cell population maintenance
GO:0035162 embryonic hemopoiesis
GO:0035234 ectopic germ cell programmed cell death
GO:0035701 hematopoietic stem cell migration
GO:0035855 megakaryocyte development
GO:0038093 Fc receptor signaling pathway
GO:0038109 Kit signaling pathway
GO:0038162 erythropoietin-mediated signaling pathway
GO:0042127 regulation of cell population proliferation
GO:0042169 SH2 domain binding
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042803 protein homodimerization activity
GO:0043069 negative regulation of programmed cell death
GO:0043235 receptor complex
GO:0043303 mast cell degranulation
GO:0043406 positive regulation of MAP kinase activity
GO:0043410 positive regulation of MAPK cascade
GO:0043473 pigmentation
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0043586 tongue development
GO:0045747 positive regulation of Notch signaling pathway
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0046686 response to cadmium ion
GO:0046777 protein autophosphorylation
GO:0046872 metal ion binding
GO:0048103 somatic stem cell division
GO:0048170 positive regulation of long-term neuronal synaptic plasticity
GO:0048565 digestive tract development
GO:0048863 stem cell differentiation
GO:0050673 epithelial cell proliferation
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051897 positive regulation of protein kinase B signaling
GO:0060326 cell chemotaxis
GO:0060374 mast cell differentiation
GO:0070662 mast cell proliferation
GO:0097067 cellular response to thyroid hormone stimulus
GO:0097324 melanocyte migration
GO:0097326 melanocyte adhesion
GO:0120072 positive regulation of pyloric antrum smooth muscle contraction
GO:1904251 regulation of bile acid metabolic process
GO:1904343 positive regulation of colon smooth muscle contraction
GO:1904349 positive regulation of small intestine smooth muscle contraction
GO:1905065 positive regulation of vascular associated smooth muscle cell differentiation

Diseases

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Interactions

8 interactions