Entity Details

Primary name CIR1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9DA19
EntryNameCIR1_MOUSE
FullNameCorepressor interacting with RBPJ 1
TaxID10090
Evidenceevidence at protein level
Length450
SequenceStatuscomplete
DateCreated2006-09-05
DateModified2021-06-02

Ontological Relatives

GenesCir1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001701 in utero embryonic development
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0016607 nuclear speck
GO:0019901 protein kinase binding
GO:0032991 protein-containing complex
GO:0042826 histone deacetylase binding
GO:0044877 protein-containing complex binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus speckle

Domains

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DomainNameCategoryType
IPR019339 CBF1-interacting co-repressor CIR, N-terminal domainDomainDomain
IPR040014 Corepressor interacting with RBPJ 1FamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CIR1_MOUSENXN_MOUSEMINT11591653 details
CIR1_MOUSERP9_MOUSEIntAct15652350 details