Entity Details

Primary name LRP5
Entity type gene
Source Source Link

Details

PrimaryID4041
RefseqGeneNG_015835
SymbolLRP5
NameLDL receptor related protein 5
Chromosome11
Location11q13.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-05-04
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsLRP5_HUMAN

GO terms

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GOName
GO:0001702 gastrulation with mouth forming second
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0002076 osteoblast development
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0006007 glucose catabolic process
GO:0006897 endocytosis
GO:0008203 cholesterol metabolic process
GO:0008217 regulation of blood pressure
GO:0008284 positive regulation of cell population proliferation
GO:0009314 response to radiation
GO:0009952 anterior/posterior pattern specification
GO:0015026 coreceptor activity
GO:0016021 integral component of membrane
GO:0017147 Wnt-protein binding
GO:0033690 positive regulation of osteoblast proliferation
GO:0035019 somatic stem cell population maintenance
GO:0035426 extracellular matrix-cell signaling
GO:0042074 cell migration involved in gastrulation
GO:0042632 cholesterol homeostasis
GO:0042733 embryonic digit morphogenesis
GO:0042813 Wnt-activated receptor activity
GO:0042981 regulation of apoptotic process
GO:0043235 receptor complex
GO:0043434 response to peptide hormone
GO:0045600 positive regulation of fat cell differentiation
GO:0045668 negative regulation of osteoblast differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0045840 positive regulation of mitotic nuclear division
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046849 bone remodeling
GO:0048539 bone marrow development
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0060033 anatomical structure regression
GO:0060042 retina morphogenesis in camera-type eye
GO:0060070 canonical Wnt signaling pathway
GO:0060349 bone morphogenesis
GO:0060444 branching involved in mammary gland duct morphogenesis
GO:0060612 adipose tissue development
GO:0060764 cell-cell signaling involved in mammary gland development
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0061304 retinal blood vessel morphogenesis
GO:0071901 negative regulation of protein serine/threonine kinase activity
GO:0071936 coreceptor activity involved in Wnt signaling pathway
GO:0110135 Norrin signaling pathway
GO:1901998 toxin transport
GO:1902262 apoptotic process involved in blood vessel morphogenesis
GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway
GO:1990851 Wnt-Frizzled-LRP5/6 complex
GO:1990909 Wnt signalosome

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
LRP5MesdUniProt15143163 details
LRP5Fzd8bhf-ucl11448771 details