Entity Details

Primary name MCM2
Entity type gene
Source Source Link

Details

PrimaryID4171
RefseqGeneNG_050771
SymbolMCM2
Nameminichromosome maintenance complex component 2
Chromosome3
Location3q21.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-20
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsMCM2_HUMAN

GO terms

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GOName
GO:0000727 double-strand break repair via break-induced replication
GO:0000781 chromosome, telomeric region
GO:0000785 chromatin
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003688 DNA replication origin binding
GO:0003697 single-stranded DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005664 nuclear origin of replication recognition complex
GO:0005737 cytoplasm
GO:0006260 DNA replication
GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006270 DNA replication initiation
GO:0006334 nucleosome assembly
GO:0006915 apoptotic process
GO:0016787 hydrolase activity
GO:0019899 enzyme binding
GO:0036388 pre-replicative complex assembly
GO:0042393 histone binding
GO:0042555 MCM complex
GO:0046872 metal ion binding
GO:0071162 CMG complex
GO:0071353 cellular response to interleukin-4
GO:0090102 cochlea development
GO:1902975 mitotic DNA replication initiation
GO:1905775 negative regulation of DNA helicase activity

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
MCM2AireIntAct20085707 details
MCM2TimelessBioGRID, IntAct26496610 details
MCM2ClspnBioGRID, IntAct26496610 details
MCM2Mcm3BioGRID, IntAct26496610 details