Entity Details

Primary name MAP3K5
Entity type gene
Source Source Link

Details

PrimaryID4217
RefseqGeneNG_011965
SymbolMAP3K5
Namemitogen-activated protein kinase kinase kinase 5
Chromosome6
Location6q23.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-15
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsM3K5_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000186 obsolete activation of MAPKK activity
GO:0000287 magnesium ion binding
GO:0002931 response to ischemia
GO:0004672 protein kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0007254 JNK cascade
GO:0007257 obsolete activation of JUN kinase activity
GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0009897 external side of plasma membrane
GO:0010666 positive regulation of cardiac muscle cell apoptotic process
GO:0016032 viral process
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0019904 protein domain specific binding
GO:0032991 protein-containing complex
GO:0034198 cellular response to amino acid starvation
GO:0034976 response to endoplasmic reticulum stress
GO:0038066 p38MAPK cascade
GO:0042060 wound healing
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043065 positive regulation of apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043507 positive regulation of JUN kinase activity
GO:0045087 innate immune response
GO:0045663 positive regulation of myoblast differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046330 positive regulation of JNK cascade
GO:0051403 stress-activated MAPK cascade
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070301 cellular response to hydrogen peroxide
GO:0071356 cellular response to tumor necrosis factor
GO:0072577 endothelial cell apoptotic process
GO:0097190 apoptotic signaling pathway
GO:0097300 programmed necrotic cell death
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1900745 positive regulation of p38MAPK cascade
GO:1901216 positive regulation of neuron death
GO:1902170 cellular response to reactive nitrogen species
GO:1902911 protein kinase complex
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:1990604 IRE1-TRAF2-ASK1 complex

Diseases

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Interactions

6 interactions