Entity Details

Primary name MET
Entity type gene
Source Source Link

Details

PrimaryID4233
RefseqGeneNG_008996
SymbolMET
NameMET proto-oncogene, receptor tyrosine kinase
Chromosome7
Location7q31.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-20
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsMET_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001886 endothelial cell morphogenesis
GO:0001889 liver development
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005008 hepatocyte growth factor-activated receptor activity
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006909 phagocytosis
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0007399 nervous system development
GO:0009925 basal plasma membrane
GO:0009986 cell surface
GO:0010507 negative regulation of autophagy
GO:0016021 integral component of membrane
GO:0016477 cell migration
GO:0017154 semaphorin receptor activity
GO:0019903 protein phosphatase binding
GO:0030182 neuron differentiation
GO:0031016 pancreas development
GO:0031116 positive regulation of microtubule polymerization
GO:0033674 positive regulation of kinase activity
GO:0035024 negative regulation of Rho protein signal transduction
GO:0035635 entry of bacterium into host cell
GO:0042802 identical protein binding
GO:0043235 receptor complex
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048754 branching morphogenesis of an epithelial tube
GO:0050918 positive chemotaxis
GO:0051497 negative regulation of stress fiber assembly
GO:0051897 positive regulation of protein kinase B signaling
GO:0061436 establishment of skin barrier
GO:0070495 negative regulation of thrombin-activated receptor signaling pathway
GO:0071526 semaphorin-plexin signaling pathway
GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death
GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity
GO:2001028 positive regulation of endothelial cell chemotaxis

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
METHgfDIP17804794 details
METGab1MINT10871282 details
METKdrIntAct22789536 details
METSpsb2DIP16369487 details