Entity Details

Primary name MIF
Entity type gene
Source Source Link

Details

PrimaryID4282
RefseqGeneNG_012099
SymbolMIF
Namemacrophage migration inhibitory factor
Chromosome22
Location22q11.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-20
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsMIF_HUMAN

GO terms

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GOName
GO:0001516 prostaglandin biosynthetic process
GO:0001819 positive regulation of cytokine production
GO:0004167 dopachrome isomerase activity
GO:0005125 cytokine activity
GO:0005126 cytokine receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006954 inflammatory response
GO:0007166 cell surface receptor signaling pathway
GO:0009986 cell surface
GO:0010629 negative regulation of gene expression
GO:0010739 positive regulation of protein kinase A signaling
GO:0010760 negative regulation of macrophage chemotaxis
GO:0019752 carboxylic acid metabolic process
GO:0030336 negative regulation of cell migration
GO:0030890 positive regulation of B cell proliferation
GO:0031982 vesicle
GO:0032760 positive regulation of tumor necrosis factor production
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0034774 secretory granule lumen
GO:0035722 interleukin-12-mediated signaling pathway
GO:0042056 chemoattractant activity
GO:0042327 positive regulation of phosphorylation
GO:0042802 identical protein binding
GO:0043030 regulation of macrophage activation
GO:0043066 negative regulation of apoptotic process
GO:0043312 neutrophil degranulation
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045087 innate immune response
GO:0048146 positive regulation of fibroblast proliferation
GO:0050178 phenylpyruvate tautomerase activity
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050900 leukocyte migration
GO:0070062 extracellular exosome
GO:0070207 protein homotrimerization
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0090344 negative regulation of cell aging
GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:1904813 ficolin-1-rich granule lumen

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
MIFBcl2l11UniProt18677096 details
MIFCsnk1eIntAct20360068 details