Entity Details

Primary name ATXN3
Entity type gene
Source Source Link

Details

PrimaryID4287
RefseqGeneNG_008198
SymbolATXN3
Nameataxin 3
Chromosome14
Location14q32.12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsATX3_HUMAN

GO terms

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GOName
GO:0000226 microtubule cytoskeleton organization
GO:0004843 thiol-dependent deubiquitinase
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006289 nucleotide-excision repair
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
GO:0007268 chemical synaptic transmission
GO:0007399 nervous system development
GO:0010810 regulation of cell-substrate adhesion
GO:0016363 nuclear matrix
GO:0016579 protein deubiquitination
GO:0030036 actin cytoskeleton organization
GO:0031625 ubiquitin protein ligase binding
GO:0031966 mitochondrial membrane
GO:0034605 cellular response to heat
GO:0035520 monoubiquitinated protein deubiquitination
GO:0042405 nuclear inclusion body
GO:0042802 identical protein binding
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045104 intermediate filament cytoskeleton organization
GO:0045202 synapse
GO:0051117 ATPase binding
GO:0061578 Lys63-specific deubiquitinase activity
GO:0070536 protein K63-linked deubiquitination
GO:0071108 protein K48-linked deubiquitination
GO:0071218 cellular response to misfolded protein
GO:1904294 positive regulation of ERAD pathway
GO:1904379 protein localization to cytosolic proteasome complex involved in ERAD pathway
GO:1990380 Lys48-specific deubiquitinase activity

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ATXN3Ubr2BioGRID30455355 details
ATXN3Pafah1b1BioGRID26496610 details
ATXN3Cep152BioGRID26496610 details