Entity Details

Primary name KMT2A
Entity type gene
Source Source Link

Details

PrimaryID4297
RefseqGeneNG_027813
SymbolKMT2A
Namelysine methyltransferase 2A
Chromosome11
Location11q23.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-20
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsKMT2A_HUMAN

GO terms

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GOName
GO:0003680 minor groove of adenine-thymine-rich DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0008270 zinc ion binding
GO:0032411 positive regulation of transporter activity
GO:0032922 circadian regulation of gene expression
GO:0035097 histone methyltransferase complex
GO:0035162 embryonic hemopoiesis
GO:0042800 histone methyltransferase activity (H3-K4 specific)
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043984 histone H4-K16 acetylation
GO:0044648 histone H3-K4 dimethylation
GO:0045322 unmethylated CpG binding
GO:0045652 regulation of megakaryocyte differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051568 histone H3-K4 methylation
GO:0051571 positive regulation of histone H3-K4 methylation
GO:0065003 protein-containing complex assembly
GO:0070577 lysine-acetylated histone binding
GO:0071339 MLL1 complex
GO:0071440 regulation of histone H3-K14 acetylation
GO:0080182 histone H3-K4 trimethylation
GO:0097692 histone H3-K4 monomethylation
GO:0106363 protein-cysteine methyltransferase activity
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:1905642 negative regulation of DNA methylation
GO:2000615 regulation of histone H3-K9 acetylation

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
KMT2AClockDIP21113167 details
KMT2AArntlDIP21113167 details
KMT2ASirt1DIP25751424 details
KMT2ACbx1BioGRID, IntAct26496610 details
KMT2ASetBioGRID, IntAct26496610 details
KMT2APik3r2BioGRID, IntAct32203420 details