Entity Details

Primary name AFDN
Entity type gene
Source Source Link

Details

PrimaryID4301
RefseqGeneNG_029689
SymbolAFDN
Nameafadin, adherens junction formation factor
Chromosome6
Location6q27
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAFAD_HUMAN

GO terms

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GOName
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0008022 protein C-terminus binding
GO:0010628 positive regulation of gene expression
GO:0016607 nuclear speck
GO:0022409 positive regulation of cell-cell adhesion
GO:0030054 cell junction
GO:0030336 negative regulation of cell migration
GO:0031267 small GTPase binding
GO:0032880 regulation of protein localization
GO:0034332 adherens junction organization
GO:0043547 positive regulation of GTPase activity
GO:0044291 cell-cell contact zone
GO:0044331 cell-cell adhesion mediated by cadherin
GO:0045296 cadherin binding
GO:0046930 pore complex
GO:0046931 pore complex assembly
GO:0050839 cell adhesion molecule binding
GO:0051015 actin filament binding
GO:0061951 establishment of protein localization to plasma membrane
GO:0070160 tight junction
GO:0070830 bicellular tight junction assembly
GO:0090557 establishment of endothelial intestinal barrier
GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
AFDNRit2IntAct10545207 details
AFDNNectin3mbinfo21880730 details
AFDNMrasBioGRID10446149 details
AFDNLats2IntAct24255178 details
AFDNRnf183BioGRID31732153 details