Entity Details

Primary name PPP1R12A
Entity type gene
Source Source Link

Details

PrimaryID4659
RefseqGene
SymbolPPP1R12A
Nameprotein phosphatase 1 regulatory subunit 12A
Chromosome12
Location12q21.2-q21.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-21
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsMYPT1_HUMAN

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0000776 kinetochore
GO:0004857 enzyme inhibitor activity
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006470 protein dephosphorylation
GO:0007098 centrosome cycle
GO:0007165 signal transduction
GO:0015629 actin cytoskeleton
GO:0019208 phosphatase regulator activity
GO:0019901 protein kinase binding
GO:0030018 Z disc
GO:0030155 regulation of cell adhesion
GO:0031672 A band
GO:0035507 regulation of myosin-light-chain-phosphatase activity
GO:0035508 positive regulation of myosin-light-chain-phosphatase activity
GO:0035690 cellular response to drug
GO:0043086 negative regulation of catalytic activity
GO:0043292 contractile fiber
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046822 regulation of nucleocytoplasmic transport
GO:0071889 14-3-3 protein binding
GO:0072357 PTW/PP1 phosphatase complex

Diseases

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Interactions

22 interactions

InteractorPartnerSourcesPublicationsLink
PPP1R12ADync1h1BioGRID, IntAct20360068 details
PPP1R12ACdk1BioGRID, IntAct20360068 details
PPP1R12APoc1bBioGRID, IntAct20360068 details
PPP1R12AErhBioGRID, IntAct20360068 details
PPP1R12ACep72BioGRID, IntAct20360068 details
PPP1R12AStag2BioGRID, IntAct20360068 details
PPP1R12ASass6BioGRID, IntAct20360068 details
PPP1R12ATrim69BioGRID, IntAct20360068 details
PPP1R12AHaus3BioGRID, IntAct20360068 details
PPP1R12ACbll1MINT22252131 details
PPP1R12APpp1cbBioGRID, IntAct26496610 details
PPP1R12AActbBioGRID, IntAct26496610 details
PPP1R12ALima1BioGRID, IntAct26496610 details
PPP1R12ACalml3BioGRID, IntAct26496610 details
PPP1R12ATmod3BioGRID, IntAct26496610 details
PPP1R12ACoro1cBioGRID, IntAct26496610 details
PPP1R12AMyh9BioGRID, IntAct26496610 details
PPP1R12AMyo1cBioGRID, IntAct26496610 details
PPP1R12AMyh10BioGRID, IntAct26496610 details
PPP1R12AKifbpBioGRID, IntAct26496610 details
PPP1R12AUso1BioGRID, IntAct26496610 details
PPP1R12ASeptin9BioGRID, IntAct26496610 details