Entity Details

Primary name NEK2
Entity type gene
Source Source Link

Details

PrimaryID4751
RefseqGeneNG_029112
SymbolNEK2
NameNIMA related kinase 2
Chromosome1
Location1q32.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-01
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNEK2_HUMAN

GO terms

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GOName
GO:0000070 mitotic sister chromatid segregation
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0000776 kinetochore
GO:0000794 condensed nuclear chromosome
GO:0000922 spindle pole
GO:0001824 blastocyst development
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005874 microtubule
GO:0006468 protein phosphorylation
GO:0007059 chromosome segregation
GO:0007088 regulation of mitotic nuclear division
GO:0007096 regulation of exit from mitosis
GO:0010389 regulation of G2/M transition of mitotic cell cycle
GO:0019903 protein phosphatase binding
GO:0030496 midbody
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0032991 protein-containing complex
GO:0043392 negative regulation of DNA binding
GO:0046602 regulation of mitotic centrosome separation
GO:0046777 protein autophosphorylation
GO:0046872 metal ion binding
GO:0051225 spindle assembly
GO:0051299 centrosome separation
GO:0051301 cell division
GO:0051321 meiotic cell cycle
GO:0051973 positive regulation of telomerase activity
GO:0051988 regulation of attachment of spindle microtubules to kinetochore
GO:0090307 mitotic spindle assembly
GO:0097711 ciliary basal body-plasma membrane docking
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1903126 negative regulation of centriole-centriole cohesion
GO:1904355 positive regulation of telomere capping

Diseases

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Interactions

7 interactions

InteractorPartnerSourcesPublicationsLink
NEK2Cdc23BioGRID, IntAct20360068 26496610 details
NEK2Nek2BioGRID, IntAct20360068 details
NEK2Cdc16BioGRID, IntAct20360068 26496610 details
NEK2Cdc26BioGRID, IntAct20360068 26496610 details
NEK2Ppp2r1aBioGRID, IntAct26496610 details
NEK2Anapc2BioGRID, IntAct26496610 details
NEK2Anapc16BioGRID, IntAct26496610 details