Entity Details

Primary name NF2
Entity type gene
Source Source Link

Details

PrimaryID4771
RefseqGeneNG_009057
SymbolNF2
Nameneurofibromin 2
Chromosome22
Location22q12.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-01-10
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsMERL_HUMAN

GO terms

Show/Hide Table
GOName
GO:0001707 mesoderm formation
GO:0001953 negative regulation of cell-matrix adhesion
GO:0003779 actin binding
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0006469 negative regulation of protein kinase activity
GO:0007398 ectoderm development
GO:0008285 negative regulation of cell population proliferation
GO:0014010 Schwann cell proliferation
GO:0014013 regulation of gliogenesis
GO:0016020 membrane
GO:0021766 hippocampus development
GO:0022408 negative regulation of cell-cell adhesion
GO:0030027 lamellipodium
GO:0030036 actin cytoskeleton organization
GO:0030336 negative regulation of cell migration
GO:0030864 cortical actin cytoskeleton
GO:0031527 filopodium membrane
GO:0031647 regulation of protein stability
GO:0032154 cleavage furrow
GO:0032587 ruffle membrane
GO:0035330 regulation of hippo signaling
GO:0042475 odontogenesis of dentin-containing tooth
GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein
GO:0042981 regulation of apoptotic process
GO:0043005 neuron projection
GO:0043409 negative regulation of MAPK cascade
GO:0044297 cell body
GO:0045177 apical part of cell
GO:0045216 cell-cell junction organization
GO:0045597 positive regulation of cell differentiation
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT
GO:0048471 perinuclear region of cytoplasm
GO:0051496 positive regulation of stress fiber assembly
GO:0051726 regulation of cell cycle
GO:0070306 lens fiber cell differentiation
GO:0072091 regulation of stem cell proliferation
GO:1900180 regulation of protein localization to nucleus
GO:2000177 regulation of neural precursor cell proliferation

Diseases

Show/Hide Table

Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
NF2Schip1BioGRID, UniProt10669747 details
NF2Ksr1BioGRID26549023 details
NF2Flot1BioGRID, IntAct26496610 details
NF2Tnks2BioGRID, IntAct26496610 details
NF2Coro1cBioGRID, IntAct26496610 details
NF2Lin7cBioGRID, IntAct26496610 details
NF2Myh9BioGRID, IntAct26496610 details
NF2Yap1BioGRID, IntAct26496610 details