Entity Details

Primary name NFKB1
Entity type gene
Source Source Link

Details

PrimaryID4790
RefseqGeneNG_050628
SymbolNFKB1
Namenuclear factor kappa B subunit 1
Chromosome4
Location4q24
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-21
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsNFKB1_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0008134 transcription factor binding
GO:0010629 negative regulation of gene expression
GO:0010744 positive regulation of macrophage derived foam cell differentiation
GO:0010884 positive regulation of lipid storage
GO:0010956 negative regulation of calcidiol 1-monooxygenase activity
GO:0010957 negative regulation of vitamin D biosynthetic process
GO:0019899 enzyme binding
GO:0031293 membrane protein intracellular domain proteolysis
GO:0032269 negative regulation of cellular protein metabolic process
GO:0032375 negative regulation of cholesterol transport
GO:0032481 positive regulation of type I interferon production
GO:0032695 negative regulation of interleukin-12 production
GO:0033256 I-kappaB/NF-kappaB complex
GO:0034774 secretory granule lumen
GO:0035580 specific granule lumen
GO:0035994 response to muscle stretch
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0042802 identical protein binding
GO:0042805 actinin binding
GO:0043066 negative regulation of apoptotic process
GO:0043312 neutrophil degranulation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050728 negative regulation of inflammatory response
GO:0050852 T cell receptor signaling pathway
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051403 stress-activated MAPK cascade
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter
GO:0070498 interleukin-1-mediated signaling pathway
GO:0071222 cellular response to lipopolysaccharide
GO:0071260 cellular response to mechanical stimulus
GO:0071316 cellular response to nicotine
GO:0071347 cellular response to interleukin-1
GO:0071354 cellular response to interleukin-6
GO:0071356 cellular response to tumor necrosis factor
GO:0071359 cellular response to dsRNA
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1900127 positive regulation of hyaluronan biosynthetic process
GO:1904385 cellular response to angiotensin
GO:2000630 positive regulation of miRNA metabolic process

Diseases

Show/Hide Table

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
NFKB1Akirin2MINT25107474 details
NFKB1Xpo1IntAct26673895 details