Entity Details

Primary name NME2
Entity type gene
Source Source Link

Details

PrimaryID4831
RefseqGene
SymbolNME2
NameNME/NM23 nucleoside diphosphate kinase 2
Chromosome17
Location17q21.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNDKB_HUMAN

GO terms

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GOName
GO:0001726 ruffle
GO:0002762 negative regulation of myeloid leukocyte differentiation
GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
GO:0004550 nucleoside diphosphate kinase activity
GO:0004673 protein histidine kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005504 fatty acid binding
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005882 intermediate filament
GO:0006165 nucleoside diphosphate phosphorylation
GO:0006183 GTP biosynthetic process
GO:0006228 UTP biosynthetic process
GO:0006241 CTP biosynthetic process
GO:0007155 cell adhesion
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0009142 nucleoside triphosphate biosynthetic process
GO:0010976 positive regulation of neuron projection development
GO:0015949 nucleobase-containing small molecule interconversion
GO:0019003 GDP binding
GO:0019215 intermediate filament binding
GO:0019899 enzyme binding
GO:0030027 lamellipodium
GO:0031966 mitochondrial membrane
GO:0034599 cellular response to oxidative stress
GO:0034774 secretory granule lumen
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043312 neutrophil degranulation
GO:0045618 positive regulation of keratinocyte differentiation
GO:0045682 regulation of epidermis development
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046777 protein autophosphorylation
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0050679 positive regulation of epithelial cell proliferation
GO:0051880 G-quadruplex DNA binding
GO:0060416 response to growth hormone
GO:0070062 extracellular exosome
GO:0071333 cellular response to glucose stimulus
GO:0071398 cellular response to fatty acid
GO:0071944 cell periphery
GO:1904813 ficolin-1-rich granule lumen

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
NME2Tubb4bIntAct20360068 details
NME2Inpp5bBioGRID, IntAct32203420 details
NME2Arhgap18BioGRID32203420 details