Entity Details

Primary name PNP
Entity type gene
Source Source Link

Details

PrimaryID4860
RefseqGeneNG_009631
SymbolPNP
Namepurine nucleoside phosphorylase
Chromosome14
Location14q11.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-05-13
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPNPH_HUMAN

GO terms

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GOName
GO:0001882 nucleoside binding
GO:0002060 purine nucleobase binding
GO:0004731 purine-nucleoside phosphorylase activity
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006139 nucleobase-containing compound metabolic process
GO:0006148 inosine catabolic process
GO:0006166 purine ribonucleoside salvage
GO:0006195 purine nucleotide catabolic process
GO:0006204 IMP catabolic process
GO:0006738 nicotinamide riboside catabolic process
GO:0006955 immune response
GO:0009165 nucleotide biosynthetic process
GO:0032743 positive regulation of interleukin-2 production
GO:0034418 urate biosynthetic process
GO:0034774 secretory granule lumen
GO:0042102 positive regulation of T cell proliferation
GO:0042301 phosphate ion binding
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0043101 purine-containing compound salvage
GO:0043312 neutrophil degranulation
GO:0046059 dAMP catabolic process
GO:0046638 positive regulation of alpha-beta T cell differentiation
GO:0047975 guanosine phosphorylase activity
GO:0070062 extracellular exosome
GO:1904813 ficolin-1-rich granule lumen

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
PNPDdb1BioGRID, IntAct26496610 details
PNPBatf3BioGRID, IntAct26496610 details
PNPTmed10BioGRID, IntAct26496610 details