Entity Details

Primary name NTHL1
Entity type gene
Source Source Link

Details

PrimaryID4913
RefseqGeneNG_008412
SymbolNTHL1
Namenth like DNA glycosylase 1
Chromosome16
Location16p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-05-27
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsNTH_HUMAN

GO terms

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GOName
GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
GO:0003684 damaged DNA binding
GO:0003690 double-stranded DNA binding
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0004519 endonuclease activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0006285 base-excision repair, AP site formation
GO:0006287 base-excision repair, gap-filling
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0019104 DNA N-glycosylase activity
GO:0045008 depyrimidination
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
NTHL1Rpl35BioGRID, IntAct26496610 details
NTHL1Gspt1BioGRID, IntAct26496610 details