Entity Details

Primary name NTRK2
Entity type gene
Source Source Link

Details

PrimaryID4915
RefseqGeneNG_012201
SymbolNTRK2
Nameneurotrophic receptor tyrosine kinase 2
Chromosome9
Location9q21.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNTRK2_HUMAN

GO terms

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GOName
GO:0001570 vasculogenesis
GO:0001764 neuron migration
GO:0001934 positive regulation of protein phosphorylation
GO:0002020 protease binding
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005030 neurotrophin receptor activity
GO:0005524 ATP binding
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007202 activation of phospholipase C activity
GO:0007275 multicellular organism development
GO:0007612 learning
GO:0007623 circadian rhythm
GO:0007631 feeding behavior
GO:0008284 positive regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0010976 positive regulation of neuron projection development
GO:0014047 glutamate secretion
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014069 postsynaptic density
GO:0019227 neuronal action potential propagation
GO:0021954 central nervous system neuron development
GO:0021987 cerebral cortex development
GO:0022011 myelination in peripheral nervous system
GO:0030182 neuron differentiation
GO:0030424 axon
GO:0030425 dendrite
GO:0031547 brain-derived neurotrophic factor receptor signaling pathway
GO:0031901 early endosome membrane
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0033674 positive regulation of kinase activity
GO:0042490 mechanoreceptor differentiation
GO:0042803 protein homodimerization activity
GO:0043087 regulation of GTPase activity
GO:0043121 neurotrophin binding
GO:0043195 terminal bouton
GO:0043197 dendritic spine
GO:0043235 receptor complex
GO:0043410 positive regulation of MAPK cascade
GO:0043524 negative regulation of neuron apoptotic process
GO:0043679 axon terminus
GO:0046548 retinal rod cell development
GO:0046777 protein autophosphorylation
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048403 brain-derived neurotrophic factor binding
GO:0048471 perinuclear region of cytoplasm
GO:0048709 oligodendrocyte differentiation
GO:0048935 peripheral nervous system neuron development
GO:0050772 positive regulation of axonogenesis
GO:0051896 regulation of protein kinase B signaling
GO:0051965 positive regulation of synapse assembly
GO:0060175 brain-derived neurotrophic factor-activated receptor activity
GO:0060291 long-term synaptic potentiation
GO:0071230 cellular response to amino acid stimulus
GO:0099183 trans-synaptic signaling by BDNF, modulating synaptic transmission
GO:0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission
GO:1902430 negative regulation of amyloid-beta formation
GO:1903997 positive regulation of non-membrane spanning protein tyrosine kinase activity
GO:1990090 cellular response to nerve growth factor stimulus
GO:1990416 cellular response to brain-derived neurotrophic factor stimulus
GO:2000811 negative regulation of anoikis

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
NTRK2BdnfBioGRID16971523 details