Entity Details

Primary name OAS3
Entity type gene
Source Source Link

Details

PrimaryID4940
RefseqGene
SymbolOAS3
Name2'-5'-oligoadenylate synthetase 3
Chromosome12
Location12q24.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-08
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsOAS3_HUMAN

GO terms

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GOName
GO:0001730 2'-5'-oligoadenylate synthetase activity
GO:0003725 double-stranded RNA binding
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006139 nucleobase-containing compound metabolic process
GO:0009615 response to virus
GO:0016020 membrane
GO:0032728 positive regulation of interferon-beta production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0035395 negative regulation of chemokine (C-X-C motif) ligand 9 production
GO:0039529 RIG-I signaling pathway
GO:0039530 MDA-5 signaling pathway
GO:0042742 defense response to bacterium
GO:0043231 intracellular membrane-bounded organelle
GO:0045071 negative regulation of viral genome replication
GO:0046872 metal ion binding
GO:0051607 defense response to virus
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060337 type I interferon signaling pathway
GO:0060339 negative regulation of type I interferon-mediated signaling pathway
GO:0060700 regulation of ribonuclease activity
GO:0071639 positive regulation of monocyte chemotactic protein-1 production
GO:0071650 negative regulation of chemokine (C-C motif) ligand 5 production
GO:0071659 negative regulation of IP-10 production
GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
OAS3Eea1BioGRID, IntAct26496610 details