Entity Details

Primary name ORC1
Entity type gene
Source Source Link

Details

PrimaryID4998
RefseqGeneNG_028251
SymbolORC1
Nameorigin recognition complex subunit 1
Chromosome1
Location1p32.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsORC1_HUMAN

GO terms

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GOName
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000781 chromosome, telomeric region
GO:0000808 origin recognition complex
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003688 DNA replication origin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005664 nuclear origin of replication recognition complex
GO:0005829 cytosol
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0016887 ATP hydrolysis activity
GO:0033314 mitotic DNA replication checkpoint signaling
GO:0036388 pre-replicative complex assembly
GO:0046872 metal ion binding

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
ORC1Orc1BioGRID, IntAct20360068 details
ORC1Cbx1BioGRID, IntAct26496610 details
ORC1AtrxBioGRID, IntAct26496610 details
ORC1Orc2BioGRID, IntAct26496610 details