Entity Details

Primary name PAK2
Entity type gene
Source Source Link

Details

PrimaryID5062
RefseqGeneNG_009227
SymbolPAK2
Namep21 (RAC1) activated kinase 2
Chromosome3
Location3q29
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-21
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsPAK2_HUMAN

GO terms

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GOName
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0006468 protein phosphorylation
GO:0006469 negative regulation of protein kinase activity
GO:0006915 apoptotic process
GO:0007165 signal transduction
GO:0014069 postsynaptic density
GO:0016310 phosphorylation
GO:0018105 peptidyl-serine phosphorylation
GO:0019901 protein kinase binding
GO:0030296 protein tyrosine kinase activator activity
GO:0031098 stress-activated protein kinase signaling cascade
GO:0031267 small GTPase binding
GO:0031295 T cell costimulation
GO:0032147 activation of protein kinase activity
GO:0034333 adherens junction assembly
GO:0035722 interleukin-12-mediated signaling pathway
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0040008 regulation of growth
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0045296 cadherin binding
GO:0046777 protein autophosphorylation
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0048471 perinuclear region of cytoplasm
GO:0050690 regulation of defense response to virus by virus
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050770 regulation of axonogenesis
GO:0050852 T cell receptor signaling pathway
GO:0051493 regulation of cytoskeleton organization
GO:0051497 negative regulation of stress fiber assembly
GO:0060996 dendritic spine development
GO:0070830 bicellular tight junction assembly
GO:0071407 cellular response to organic cyclic compound
GO:0098978 glutamatergic synapse
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:0150105 protein localization to cell-cell junction
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway
GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PAK2Racgap1BioGRID, IntAct26496610 details
PAK2Myl12bIntAct26496610 details