Entity Details

Primary name FOXP3
Entity type gene
Source Source Link

Details

PrimaryID50943
RefseqGeneNG_007392
SymbolFOXP3
Nameforkhead box P3
ChromosomeX
LocationXp11.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-08
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsFOXP3_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001782 B cell homeostasis
GO:0001818 negative regulation of cytokine production
GO:0002262 myeloid cell homeostasis
GO:0002362 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment
GO:0002456 T cell mediated immunity
GO:0002513 tolerance induction to self antigen
GO:0002667 regulation of T cell anergy
GO:0002669 positive regulation of T cell anergy
GO:0002677 negative regulation of chronic inflammatory response
GO:0002725 negative regulation of T cell cytokine production
GO:0002851 positive regulation of peripheral T cell tolerance induction
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006338 chromatin remodeling
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008285 negative regulation of cell population proliferation
GO:0009314 response to radiation
GO:0009615 response to virus
GO:0010467 gene expression
GO:0014045 establishment of endothelial blood-brain barrier
GO:0030111 regulation of Wnt signaling pathway
GO:0031064 negative regulation of histone deacetylation
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032496 response to lipopolysaccharide
GO:0032689 negative regulation of interferon-gamma production
GO:0032693 negative regulation of interleukin-10 production
GO:0032700 negative regulation of interleukin-17 production
GO:0032703 negative regulation of interleukin-2 production
GO:0032713 negative regulation of interleukin-4 production
GO:0032714 negative regulation of interleukin-5 production
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032753 positive regulation of interleukin-4 production
GO:0032792 negative regulation of CREB transcription factor activity
GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0032914 positive regulation of transforming growth factor beta1 production
GO:0032991 protein-containing complex
GO:0033092 positive regulation of immature T cell proliferation in thymus
GO:0035035 histone acetyltransferase binding
GO:0035066 positive regulation of histone acetylation
GO:0035067 negative regulation of histone acetylation
GO:0042110 T cell activation
GO:0042130 negative regulation of T cell proliferation
GO:0042803 protein homodimerization activity
GO:0042826 histone deacetylase binding
GO:0043029 T cell homeostasis
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0045589 regulation of regulatory T cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046007 negative regulation of activated T cell proliferation
GO:0046872 metal ion binding
GO:0048294 negative regulation of isotype switching to IgE isotypes
GO:0048302 regulation of isotype switching to IgG isotypes
GO:0050687 negative regulation of defense response to virus
GO:0050777 negative regulation of immune response
GO:0050852 T cell receptor signaling pathway
GO:0051059 NF-kappaB binding
GO:0051525 NFAT protein binding
GO:1901355 response to rapamycin
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000320 negative regulation of T-helper 17 cell differentiation

Diseases

Show/Hide Table

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
FOXP3Il2IntAct16873067 details
FOXP3Il2raIntAct16873067 details