Entity Details

Primary name EXOSC3
Entity type gene
Source Source Link

Details

PrimaryID51010
RefseqGeneNG_032780
SymbolEXOSC3
Nameexosome component 3
Chromosome9
Location9p13.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-30
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsEXOS3_HUMAN

GO terms

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GOName
GO:0000175 3'-5'-exoribonuclease activity
GO:0000176 nuclear exosome (RNase complex)
GO:0000177 cytoplasmic exosome (RNase complex)
GO:0000178 exosome (RNase complex)
GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006364 rRNA processing
GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
GO:0034475 U4 snRNA 3'-end processing
GO:0035327 transcriptionally active chromatin
GO:0043488 regulation of mRNA stability
GO:0043928 exonucleolytic catabolism of deadenylated mRNA
GO:0045006 DNA deamination
GO:0045190 isotype switching
GO:0045830 positive regulation of isotype switching
GO:0071034 CUT catabolic process
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic process
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic process
GO:0071049 nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription
GO:0071051 polyadenylation-dependent snoRNA 3'-end processing

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
EXOSC3AicdaIntAct21255825 details
EXOSC3Exosc1BioGRID, IntAct26496610 details