Entity Details

Primary name IRAK4
Entity type gene
Source Source Link

Details

PrimaryID51135
RefseqGeneNG_009892
SymbolIRAK4
Nameinterleukin 1 receptor associated kinase 4
Chromosome12
Location12q12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-08
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsIRAK4_HUMAN

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0002224 toll-like receptor signaling pathway
GO:0002446 neutrophil mediated immunity
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0004674 protein serine/threonine kinase activity
GO:0005149 interleukin-1 receptor binding
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007254 JNK cascade
GO:0010008 endosome membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0034162 toll-like receptor 9 signaling pathway
GO:0035556 intracellular signal transduction
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 innate immune response
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0070498 interleukin-1-mediated signaling pathway
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1990266 neutrophil migration

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
IRAK4Irak3MINT23376919 details