Entity Details

Primary name LARS1
Entity type gene
Source Source Link

Details

PrimaryID51520
RefseqGeneNG_042294
SymbolLARS1
Nameleucyl-tRNA synthetase 1
Chromosome5
Location5q32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-11
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSYLC_HUMAN

GO terms

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GOName
GO:0002161 aminoacyl-tRNA editing activity
GO:0004819 glutamine-tRNA ligase activity
GO:0004823 leucine-tRNA ligase activity
GO:0005096 GTPase activator activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0006418 tRNA aminoacylation for protein translation
GO:0006425 glutaminyl-tRNA aminoacylation
GO:0006429 leucyl-tRNA aminoacylation
GO:0008361 regulation of cell size
GO:0012505 endomembrane system
GO:0016604 nuclear body
GO:0017101 aminoacyl-tRNA synthetase multienzyme complex
GO:0032008 positive regulation of TOR signaling
GO:0034198 cellular response to amino acid starvation
GO:0043547 positive regulation of GTPase activity
GO:0071230 cellular response to amino acid stimulus
GO:0071233 cellular response to leucine
GO:1904263 positive regulation of TORC1 signaling
GO:1990253 cellular response to leucine starvation

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
LARS1Eef1a1BioGRID, IntAct26496610 details
LARS1Sdccag8BioGRID, IntAct26496610 details
LARS1MecomMINT30462309 details
LARS1Ktn1BioGRID26496610 details
LARS1Rnf183BioGRID31732153 details