Entity Details

Primary name PDGFRB
Entity type gene
Source Source Link

Details

PrimaryID5159
RefseqGeneNG_023367
SymbolPDGFRB
Nameplatelet derived growth factor receptor beta
Chromosome5
Location5q32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-21
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsPGFRB_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004992 platelet activating factor receptor activity
GO:0005017 platelet-derived growth factor-activated receptor activity
GO:0005019 platelet-derived growth factor beta-receptor activity
GO:0005102 signaling receptor binding
GO:0005161 platelet-derived growth factor receptor binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005925 focal adhesion
GO:0006024 glycosaminoglycan biosynthetic process
GO:0007165 signal transduction
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0007568 aging
GO:0008284 positive regulation of cell population proliferation
GO:0008584 male gonad development
GO:0009636 response to toxic substance
GO:0009986 cell surface
GO:0010863 positive regulation of phospholipase C activity
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014911 positive regulation of smooth muscle cell migration
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0016477 cell migration
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019838 growth factor binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030335 positive regulation of cell migration
GO:0031226 intrinsic component of plasma membrane
GO:0031410 cytoplasmic vesicle
GO:0032355 response to estradiol
GO:0032516 positive regulation of phosphoprotein phosphatase activity
GO:0032526 response to retinoic acid
GO:0032956 regulation of actin cytoskeleton organization
GO:0032967 positive regulation of collagen biosynthetic process
GO:0033674 positive regulation of kinase activity
GO:0034405 response to fluid shear stress
GO:0035025 positive regulation of Rho protein signal transduction
GO:0035441 cell migration involved in vasculogenesis
GO:0035789 metanephric mesenchymal cell migration
GO:0035791 platelet-derived growth factor receptor-beta signaling pathway
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
GO:0035909 aorta morphogenesis
GO:0038085 vascular endothelial growth factor binding
GO:0038091 positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
GO:0042060 wound healing
GO:0042542 response to hydrogen peroxide
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043202 lysosomal lumen
GO:0043231 intracellular membrane-bounded organelle
GO:0043235 receptor complex
GO:0043406 positive regulation of MAP kinase activity
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0043627 response to estrogen
GO:0045840 positive regulation of mitotic nuclear division
GO:0046488 phosphatidylinositol metabolic process
GO:0046777 protein autophosphorylation
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0048015 phosphatidylinositol-mediated signaling
GO:0048146 positive regulation of fibroblast proliferation
GO:0048407 platelet-derived growth factor binding
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0048839 inner ear development
GO:0050921 positive regulation of chemotaxis
GO:0051897 positive regulation of protein kinase B signaling
GO:0055003 cardiac myofibril assembly
GO:0055093 response to hyperoxia
GO:0060326 cell chemotaxis
GO:0060437 lung growth
GO:0060981 cell migration involved in coronary angiogenesis
GO:0061298 retina vasculature development in camera-type eye
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071670 smooth muscle cell chemotaxis
GO:0072075 metanephric mesenchyme development
GO:0072262 metanephric glomerular mesangial cell proliferation involved in metanephros development
GO:0072277 metanephric glomerular capillary formation
GO:0072278 metanephric comma-shaped body morphogenesis
GO:0072284 metanephric S-shaped body morphogenesis
GO:0090280 positive regulation of calcium ion import
GO:2000379 positive regulation of reactive oxygen species metabolic process
GO:2000491 positive regulation of hepatic stellate cell activation
GO:2000573 positive regulation of DNA biosynthetic process

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PDGFRBKdrDIP18997771 details