Entity Details

Primary name PDPK1
Entity type gene
Source Source Link

Details

PrimaryID5170
RefseqGene
SymbolPDPK1
Name3-phosphoinositide dependent protein kinase 1
Chromosome16
Location16p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-03-23
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPDPK1_HUMAN

GO terms

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GOName
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0003323 type B pancreatic cell development
GO:0004674 protein serine/threonine kinase activity
GO:0004676 3-phosphoinositide-dependent protein kinase activity
GO:0005158 insulin receptor binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006468 protein phosphorylation
GO:0006469 negative regulation of protein kinase activity
GO:0006972 hyperosmotic response
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0010518 positive regulation of phospholipase activity
GO:0010667 negative regulation of cardiac muscle cell apoptotic process
GO:0014069 postsynaptic density
GO:0016004 phospholipase activator activity
GO:0016477 cell migration
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0019722 calcium-mediated signaling
GO:0019901 protein kinase binding
GO:0030036 actin cytoskeleton organization
GO:0030168 platelet activation
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0031295 T cell costimulation
GO:0031410 cytoplasmic vesicle
GO:0032148 activation of protein kinase B activity
GO:0032869 cellular response to insulin stimulus
GO:0034122 negative regulation of toll-like receptor signaling pathway
GO:0035556 intracellular signal transduction
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0042995 cell projection
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043204 perikaryon
GO:0043274 phospholipase binding
GO:0043304 regulation of mast cell degranulation
GO:0043524 negative regulation of neuron apoptotic process
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0045766 positive regulation of angiogenesis
GO:0046777 protein autophosphorylation
GO:0048041 focal adhesion assembly
GO:0050852 T cell receptor signaling pathway
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0051897 positive regulation of protein kinase B signaling
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0097191 extrinsic apoptotic signaling pathway
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901796 regulation of signal transduction by p53 class mediator
GO:1903078 positive regulation of protein localization to plasma membrane
GO:1903672 positive regulation of sprouting angiogenesis
GO:1905564 positive regulation of vascular endothelial cell proliferation
GO:1990416 cellular response to brain-derived neurotrophic factor stimulus
GO:2000352 negative regulation of endothelial cell apoptotic process

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
PDPK1Akt1BioGRID19662498 details
PDPK1Kctd5BioGRID, IntAct26496610 details
PDPK1Cct2BioGRID, IntAct26496610 details
PDPK1Xpo1IntAct26673895 details