Entity Details

Primary name WWOX
Entity type gene
Source Source Link

Details

PrimaryID51741
RefseqGeneNG_011698
SymbolWWOX
NameWW domain containing oxidoreductase
Chromosome16
Location16q23.1-q23.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-07-07
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsWWOX_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001649 osteoblast differentiation
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0016055 Wnt signaling pathway
GO:0016491 oxidoreductase activity
GO:0019899 enzyme binding
GO:0030178 negative regulation of Wnt signaling pathway
GO:0042802 identical protein binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048705 skeletal system morphogenesis
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:0090575 RNA polymerase II transcription regulator complex
GO:0097191 extrinsic apoptotic signaling pathway
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway
GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
WWOXErbb4IntAct16061658 details
WWOXBcl9lIntAct25678599 details
WWOXDvl2IntAct25678599 details
WWOXRnf183BioGRID31732153 details