Entity Details

Primary name CSKP_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO70589
EntryNameCSKP_MOUSE
FullNamePeripheral plasma membrane protein CASK
TaxID10090
Evidenceevidence at protein level
Length926
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesCask

GO terms

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GOName
GO:0001953 negative regulation of cell-matrix adhesion
GO:0004674 protein serine/threonine kinase activity
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005604 basement membrane
GO:0005634 nucleus
GO:0005652 nuclear lamina
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008022 protein C-terminus binding
GO:0010839 negative regulation of keratinocyte proliferation
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0016323 basolateral plasma membrane
GO:0016363 nuclear matrix
GO:0030165 PDZ domain binding
GO:0030425 dendrite
GO:0031982 vesicle
GO:0032024 positive regulation of insulin secretion
GO:0032991 protein-containing complex
GO:0042043 neurexin family protein binding
GO:0042734 presynaptic membrane
GO:0043025 neuronal cell body
GO:0044877 protein-containing complex binding
GO:0045121 membrane raft
GO:0045202 synapse
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048471 perinuclear region of cytoplasm
GO:0060170 ciliary membrane
GO:0061003 positive regulation of dendritic spine morphogenesis
GO:0061045 negative regulation of wound healing
GO:0070509 calcium ion import
GO:0072659 protein localization to plasma membrane
GO:0090280 positive regulation of calcium ion import
GO:0090288 negative regulation of cellular response to growth factor stimulus
GO:0097060 synaptic membrane
GO:0097440 apical dendrite
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098846 podocyte foot
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000300 regulation of synaptic vesicle exocytosis

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR004172 L27 domainDomainDomain
IPR008144 Guanylate kinase-like domainDomainDomain
IPR008145 Guanylate kinase/L-type calcium channel beta subunitDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR014775 L27 domain, C-terminalDomainDomain
IPR020590 Guanylate kinase, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR035473 CASK, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR036892 L27 domain superfamilyFamilyHomologous superfamily

Diseases

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