Entity Details

Primary name XRN2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ9DBR1
EntryNameXRN2_MOUSE
FullName5'-3' exoribonuclease 2
TaxID10090
Evidenceevidence at protein level
Length951
SequenceStatuscomplete
DateCreated2003-04-23
DateModified2021-06-02

Ontological Relatives

GenesXrn2

GO terms

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GOName
GO:0000175 3'-5'-exoribonuclease activity
GO:0000738 DNA catabolic process, exonucleolytic
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0001147 transcription termination site sequence-specific DNA binding
GO:0003723 RNA binding
GO:0004534 5'-3' exoribonuclease activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006397 mRNA processing
GO:0007017 microtubule-based process
GO:0007283 spermatogenesis
GO:0008409 5'-3' exonuclease activity
GO:0016070 RNA metabolic process
GO:0016235 aggresome
GO:0021766 hippocampus development
GO:0030182 neuron differentiation
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0060041 retina development in camera-type eye

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR004859 Putative 5-3 exonucleaseDomainDomain
IPR017151 5'-3' exoribonuclease type 2FamilyFamily
IPR027073 5'-3' exoribonucleaseFamilyFamily
IPR041412 Xrn1, helical domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
XRN2_MOUSEAAPK1_HUMANBioGRID, IntAct20368287 details
XRN2_MOUSEOGG1_MOUSEBioGRID22057269 details