Entity Details

Primary name PKD2
Entity type gene
Source Source Link

Details

PrimaryID5311
RefseqGeneNG_008604
SymbolPKD2
Namepolycystin 2, transient receptor potential cation channel
Chromosome4
Location4q22.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-02-07
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsPKD2_HUMAN

GO terms

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GOName
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001889 liver development
GO:0001892 embryonic placenta development
GO:0001947 heart looping
GO:0002133 polycystin complex
GO:0003127 detection of nodal flow
GO:0005102 signaling receptor binding
GO:0005244 voltage-gated ion channel activity
GO:0005245 voltage-gated calcium channel activity
GO:0005248 voltage-gated sodium channel activity
GO:0005249 voltage-gated potassium channel activity
GO:0005261 cation channel activity
GO:0005267 potassium channel activity
GO:0005509 calcium ion binding
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0005929 cilium
GO:0006816 calcium ion transport
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0007368 determination of left/right symmetry
GO:0007507 heart development
GO:0008092 cytoskeletal protein binding
GO:0008285 negative regulation of cell population proliferation
GO:0009925 basal plasma membrane
GO:0010628 positive regulation of gene expression
GO:0015271 outward rectifier potassium channel activity
GO:0016020 membrane
GO:0016055 Wnt signaling pathway
GO:0016323 basolateral plasma membrane
GO:0021510 spinal cord development
GO:0021915 neural tube development
GO:0022843 voltage-gated cation channel activity
GO:0030027 lamellipodium
GO:0030659 cytoplasmic vesicle membrane
GO:0031514 motile cilium
GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0034614 cellular response to reactive oxygen species
GO:0034703 cation channel complex
GO:0035502 metanephric part of ureteric bud development
GO:0035725 sodium ion transmembrane transport
GO:0035904 aorta development
GO:0036064 ciliary basal body
GO:0042127 regulation of cell population proliferation
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042805 actinin binding
GO:0042994 cytoplasmic sequestering of transcription factor
GO:0043398 HLH domain binding
GO:0044325 transmembrane transporter binding
GO:0044782 cilium organization
GO:0045180 basal cortex
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048763 calcium-induced calcium release activity
GO:0050982 detection of mechanical stimulus
GO:0051117 ATPase binding
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051219 phosphoprotein binding
GO:0051262 protein tetramerization
GO:0051289 protein homotetramerization
GO:0051290 protein heterotetramerization
GO:0051298 centrosome duplication
GO:0051371 muscle alpha-actinin binding
GO:0060170 ciliary membrane
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0060674 placenta blood vessel development
GO:0061333 renal tubule morphogenesis
GO:0061441 renal artery morphogenesis
GO:0070062 extracellular exosome
GO:0070588 calcium ion transmembrane transport
GO:0071277 cellular response to calcium ion
GO:0071320 cellular response to cAMP
GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071464 cellular response to hydrostatic pressure
GO:0071470 cellular response to osmotic stress
GO:0071498 cellular response to fluid shear stress
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane
GO:0071805 potassium ion transmembrane transport
GO:0071910 determination of liver left/right asymmetry
GO:0072075 metanephric mesenchyme development
GO:0072164 mesonephric tubule development
GO:0072177 mesonephric duct development
GO:0072208 metanephric smooth muscle tissue development
GO:0072214 metanephric cortex development
GO:0072218 metanephric ascending thin limb development
GO:0072219 metanephric cortical collecting duct development
GO:0072235 metanephric distal tubule development
GO:0072284 metanephric S-shaped body morphogenesis
GO:0072686 mitotic spindle
GO:0090279 regulation of calcium ion import
GO:0097730 non-motile cilium
GO:0098662 inorganic cation transmembrane transport
GO:0198738 cell-cell signaling by wnt
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle

Diseases

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Interactions

8 interactions