Entity Details

Primary name PKP2
Entity type gene
Source Source Link

Details

PrimaryID5318
RefseqGeneNG_009000
SymbolPKP2
Nameplakophilin 2
Chromosome12
Location12p11.21
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-28
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsPKP2_HUMAN

GO terms

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GOName
GO:0001533 cornified envelope
GO:0002159 desmosome assembly
GO:0002934 desmosome organization
GO:0005080 protein kinase C binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005882 intermediate filament
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0007043 cell-cell junction assembly
GO:0007507 heart development
GO:0010765 positive regulation of sodium ion transport
GO:0014704 intercalated disc
GO:0016021 integral component of membrane
GO:0017080 sodium channel regulator activity
GO:0019215 intermediate filament binding
GO:0030054 cell junction
GO:0030057 desmosome
GO:0031424 keratinization
GO:0044325 transmembrane transporter binding
GO:0045110 intermediate filament bundle assembly
GO:0045294 alpha-catenin binding
GO:0045296 cadherin binding
GO:0048496 maintenance of animal organ identity
GO:0055010 ventricular cardiac muscle tissue morphogenesis
GO:0060090 molecular adaptor activity
GO:0070268 cornification
GO:0072659 protein localization to plasma membrane
GO:0086002 cardiac muscle cell action potential involved in contraction
GO:0086005 ventricular cardiac muscle cell action potential
GO:0086019 cell-cell signaling involved in cardiac conduction
GO:0086064 cell communication by electrical coupling involved in cardiac conduction
GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication
GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
GO:0086091 regulation of heart rate by cardiac conduction
GO:0098609 cell-cell adhesion
GO:0098911 regulation of ventricular cardiac muscle cell action potential

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PKP2Uso1BioGRID, IntAct26496610 details
PKP2Dppa3BioGRID28712289 details