Entity Details

Primary name PLCG1
Entity type gene
Source Source Link

Details

PrimaryID5335
RefseqGene
SymbolPLCG1
Namephospholipase C gamma 1
Chromosome20
Location20q12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-05-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPLCG1_HUMAN

GO terms

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GOName
GO:0001701 in utero embryonic development
GO:0001726 ruffle
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0005168 neurotrophin TRKA receptor binding
GO:0005509 calcium ion binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0007165 signal transduction
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007202 activation of phospholipase C activity
GO:0007411 axon guidance
GO:0008180 COP9 signalosome
GO:0009395 phospholipid catabolic process
GO:0010634 positive regulation of epithelial cell migration
GO:0010863 positive regulation of phospholipase C activity
GO:0016032 viral process
GO:0016477 cell migration
GO:0019722 calcium-mediated signaling
GO:0019901 protein kinase binding
GO:0030027 lamellipodium
GO:0030971 receptor tyrosine kinase binding
GO:0035254 glutamate receptor binding
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0042995 cell projection
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0043647 inositol phosphate metabolic process
GO:0045766 positive regulation of angiogenesis
GO:0046488 phosphatidylinositol metabolic process
GO:0050429 calcium-dependent phospholipase C activity
GO:0050804 modulation of chemical synaptic transmission
GO:0050852 T cell receptor signaling pathway
GO:0050900 leukocyte migration
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098978 glutamatergic synapse
GO:1905564 positive regulation of vascular endothelial cell proliferation
GO:2000353 positive regulation of endothelial cell apoptotic process

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
PLCG1LeprBioGRID18165436 details
PLCG1Dnm2mbinfo11018064 details
PLCG1Tespa1InnateDB22561606 details