Entity Details

Primary name PLCG2
Entity type gene
Source Source Link

Details

PrimaryID5336
RefseqGeneNG_032019
SymbolPLCG2
Namephospholipase C gamma 2
Chromosome16
Location16q23.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-01-05
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPLCG2_HUMAN

GO terms

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GOName
GO:0001784 phosphotyrosine residue binding
GO:0002092 positive regulation of receptor internalization
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002316 follicular B cell differentiation
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006661 phosphatidylinositol biosynthetic process
GO:0009395 phospholipid catabolic process
GO:0010628 positive regulation of gene expression
GO:0010634 positive regulation of epithelial cell migration
GO:0016055 Wnt signaling pathway
GO:0019722 calcium-mediated signaling
GO:0019901 protein kinase binding
GO:0030168 platelet activation
GO:0030183 B cell differentiation
GO:0032237 activation of store-operated calcium channel activity
GO:0032481 positive regulation of type I interferon production
GO:0032496 response to lipopolysaccharide
GO:0032959 inositol trisphosphate biosynthetic process
GO:0035556 intracellular signal transduction
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043069 negative regulation of programmed cell death
GO:0043647 inositol phosphate metabolic process
GO:0050852 T cell receptor signaling pathway
GO:0050853 B cell receptor signaling pathway
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051209 release of sequestered calcium ion into cytosol
GO:0070062 extracellular exosome
GO:0071277 cellular response to calcium ion
GO:0097110 scaffold protein binding
GO:0140031 phosphorylation-dependent protein binding
GO:1902808 positive regulation of cell cycle G1/S phase transition

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PLCG2CskBioGRID, IntAct26496610 details