Entity Details

Primary name PMAIP1
Entity type gene
Source Source Link

Details

PrimaryID5366
RefseqGene
SymbolPMAIP1
Namephorbol-12-myristate-13-acetate-induced protein 1
Chromosome18
Location18q21.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAPR_HUMAN

GO terms

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GOName
GO:0001836 release of cytochrome c from mitochondria
GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0010498 proteasomal protein catabolic process
GO:0010907 positive regulation of glucose metabolic process
GO:0010917 negative regulation of mitochondrial membrane potential
GO:0042149 cellular response to glucose starvation
GO:0042981 regulation of apoptotic process
GO:0043029 T cell homeostasis
GO:0043065 positive regulation of apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043331 response to dsRNA
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0046902 regulation of mitochondrial membrane permeability
GO:0051607 defense response to virus
GO:0071456 cellular response to hypoxia
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:0072593 reactive oxygen species metabolic process
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:0097193 intrinsic apoptotic signaling pathway
GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PMAIP1Mcl1BioGRID, IntAct15694340 32094511 details
PMAIP1Bcl2a1aIntAct15694340 details