Entity Details

Primary name XRN1
Entity type gene
Source Source Link

Details

PrimaryID54464
RefseqGene
SymbolXRN1
Name5'-3' exoribonuclease 1
Chromosome3
Location3q23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-06-26
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsXRN1_HUMAN

GO terms

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GOName
GO:0000932 P-body
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0002151 G-quadruplex RNA binding
GO:0003723 RNA binding
GO:0004534 5'-3' exoribonuclease activity
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016075 rRNA catabolic process
GO:0017148 negative regulation of translation
GO:0030425 dendrite
GO:0032211 negative regulation of telomere maintenance via telomerase
GO:0033574 response to testosterone
GO:0043025 neuronal cell body
GO:0043488 regulation of mRNA stability
GO:0045202 synapse
GO:0051880 G-quadruplex DNA binding
GO:0070034 telomerase RNA binding
GO:0071028 nuclear mRNA surveillance
GO:0071044 histone mRNA catabolic process
GO:0071409 cellular response to cycloheximide
GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic
GO:1905795 cellular response to puromycin

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
XRN1Cdk1BioGRID, IntAct26496610 details
XRN1Naa50BioGRID, IntAct26496610 details
XRN1Xpo1IntAct26673895 details
XRN1MeiocUniProt26742488 details
XRN1Rnf183BioGRID31732153 details