Entity Details

Primary name PAF1
Entity type gene
Source Source Link

Details

PrimaryID54623
RefseqGene
SymbolPAF1
NamePAF1 homolog, Paf1/RNA polymerase II complex component
Chromosome19
Location19q13.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-08-26
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPAF1_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000993 RNA polymerase II complex binding
GO:0001711 endodermal cell fate commitment
GO:0003682 chromatin binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006366 transcription by RNA polymerase II
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0006378 mRNA polyadenylation
GO:0010390 histone monoubiquitination
GO:0016020 membrane
GO:0016055 Wnt signaling pathway
GO:0016567 protein ubiquitination
GO:0016584 nucleosome positioning
GO:0016593 Cdc73/Paf1 complex
GO:0019827 stem cell population maintenance
GO:0030054 cell junction
GO:0031062 positive regulation of histone methylation
GO:0031442 positive regulation of mRNA 3'-end processing
GO:0033523 histone H2B ubiquitination
GO:0034504 protein localization to nucleus
GO:0035327 transcriptionally active chromatin
GO:0045638 negative regulation of myeloid cell differentiation
GO:0071222 cellular response to lipopolysaccharide
GO:1902808 positive regulation of cell cycle G1/S phase transition

Diseases

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Interactions

7 interactions

InteractorPartnerSourcesPublicationsLink
PAF1Rprd1bBioGRID, IntAct26496610 details
PAF1Wdr61BioGRID, IntAct26496610 details
PAF1Tox4BioGRID, IntAct26496610 details
PAF1Xpo1IntAct26673895 details
PAF1Prdm16MINT30462309 details
PAF1MecomMINT30462309 details
PAF1Ksr1BioGRID26549023 details