Entity Details

Primary name PPARG
Entity type gene
Source Source Link

Details

PrimaryID5468
RefseqGeneNG_011749
SymbolPPARG
Nameperoxisome proliferator activated receptor gamma
Chromosome3
Location3p25.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsPPARG_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001890 placenta development
GO:0002674 negative regulation of acute inflammatory response
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0004879 nuclear receptor activity
GO:0004955 prostaglandin receptor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006629 lipid metabolic process
GO:0006631 fatty acid metabolic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007165 signal transduction
GO:0007507 heart development
GO:0007584 response to nutrient
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0008217 regulation of blood pressure
GO:0008270 zinc ion binding
GO:0009409 response to cold
GO:0009612 response to mechanical stimulus
GO:0009755 hormone-mediated signaling pathway
GO:0010742 macrophage derived foam cell differentiation
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010887 negative regulation of cholesterol storage
GO:0010891 negative regulation of sequestering of triglyceride
GO:0015909 long-chain fatty acid transport
GO:0016525 negative regulation of angiogenesis
GO:0019216 regulation of lipid metabolic process
GO:0019395 fatty acid oxidation
GO:0019899 enzyme binding
GO:0019903 protein phosphatase binding
GO:0030154 cell differentiation
GO:0030224 monocyte differentiation
GO:0030308 negative regulation of cell growth
GO:0030331 estrogen receptor binding
GO:0030514 negative regulation of BMP signaling pathway
GO:0030855 epithelial cell differentiation
GO:0031000 response to caffeine
GO:0031100 animal organ regeneration
GO:0032869 cellular response to insulin stimulus
GO:0032966 negative regulation of collagen biosynthetic process
GO:0033189 response to vitamin A
GO:0033993 response to lipid
GO:0035357 peroxisome proliferator activated receptor signaling pathway
GO:0035902 response to immobilization stress
GO:0042277 peptide binding
GO:0042493 response to drug
GO:0042593 glucose homeostasis
GO:0042594 response to starvation
GO:0042752 regulation of circadian rhythm
GO:0042802 identical protein binding
GO:0042953 lipoprotein transport
GO:0043231 intracellular membrane-bounded organelle
GO:0043235 receptor complex
GO:0043388 positive regulation of DNA binding
GO:0043537 negative regulation of blood vessel endothelial cell migration
GO:0043621 protein self-association
GO:0043627 response to estrogen
GO:0045087 innate immune response
GO:0045165 cell fate commitment
GO:0045600 positive regulation of fat cell differentiation
GO:0045668 negative regulation of osteoblast differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045923 positive regulation of fatty acid metabolic process
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046321 positive regulation of fatty acid oxidation
GO:0046965 retinoid X receptor binding
GO:0048384 retinoic acid receptor signaling pathway
GO:0048469 cell maturation
GO:0048471 perinuclear region of cytoplasm
GO:0048511 rhythmic process
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0048714 positive regulation of oligodendrocyte differentiation
GO:0050544 arachidonic acid binding
GO:0050692 DNA binding domain binding
GO:0050693 LBD domain binding
GO:0050728 negative regulation of inflammatory response
GO:0050872 white fat cell differentiation
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051393 alpha-actinin binding
GO:0051974 negative regulation of telomerase activity
GO:0055088 lipid homeostasis
GO:0060100 positive regulation of phagocytosis, engulfment
GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway
GO:0060694 regulation of cholesterol transporter activity
GO:0060965 negative regulation of gene silencing by miRNA
GO:0070888 E-box binding
GO:0071300 cellular response to retinoic acid
GO:0071306 cellular response to vitamin E
GO:0071380 cellular response to prostaglandin E stimulus
GO:0071404 cellular response to low-density lipoprotein particle stimulus
GO:0071455 cellular response to hyperoxia
GO:0090575 RNA polymerase II transcription regulator complex
GO:1901558 response to metformin
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation
GO:1905461 positive regulation of vascular associated smooth muscle cell apoptotic process
GO:1905563 negative regulation of vascular endothelial cell proliferation
GO:1905599 positive regulation of low-density lipoprotein receptor activity
GO:2000230 negative regulation of pancreatic stellate cell proliferation
GO:2000272 negative regulation of signaling receptor activity

Diseases

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Interactions

6 interactions