Entity Details

Primary name PPM1A
Entity type gene
Source Source Link

Details

PrimaryID5494
RefseqGeneNG_029698
SymbolPPM1A
Nameprotein phosphatase, Mg2+/Mn2+ dependent 1A
Chromosome14
Location14q23.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1993-02-10
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPPM1A_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000287 magnesium ion binding
GO:0004722 protein serine/threonine phosphatase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006470 protein dephosphorylation
GO:0006499 N-terminal protein myristoylation
GO:0010991 negative regulation of SMAD protein complex assembly
GO:0016020 membrane
GO:0016311 dephosphorylation
GO:0030145 manganese ion binding
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0033192 calmodulin-dependent protein phosphatase activity
GO:0035970 peptidyl-threonine dephosphorylation
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046827 positive regulation of protein export from nucleus
GO:0070412 R-SMAD binding
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity
GO:1901223 negative regulation of NIK/NF-kappaB signaling

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PPM1ACbll1MINT22252131 details
PPM1ACsnk1dBioGRID, IntAct26496610 details