Entity Details

Primary name PPM1B
Entity type gene
Source Source Link

Details

PrimaryID5495
RefseqGeneNG_011678
SymbolPPM1B
Nameprotein phosphatase, Mg2+/Mn2+ dependent 1B
Chromosome2
Location2p21
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-12-16
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPPM1B_HUMAN

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004722 protein serine/threonine phosphatase activity
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0006470 protein dephosphorylation
GO:0006499 N-terminal protein myristoylation
GO:0016020 membrane
GO:0030145 manganese ion binding
GO:0032688 negative regulation of interferon-beta production
GO:0035970 peptidyl-threonine dephosphorylation
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050687 negative regulation of defense response to virus
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity
GO:1901223 negative regulation of NIK/NF-kappaB signaling

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
PPM1BSmurf2BioGRID, IntAct19379695 details
PPM1BCbll1MINT22252131 details
PPM1BXpo1IntAct26673895 details